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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA6 All Species: 28.48
Human Site: S1542 Identified Species: 62.67
UniProt: Q8N139 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N139 NP_525023.2 1617 184286 S1542 A G Q E R Y S S L L T Y K L P
Chimpanzee Pan troglodytes XP_001146278 1564 178469 S1489 A G Q E R Y S S L L T Y K L P
Rhesus Macaque Macaca mulatta XP_001083010 1618 184304 S1543 A G Q E R Y S S L L T Y K L P
Dog Lupus familis XP_850922 1621 183954 S1546 A Q Q E R Y S S L L V Y K L P
Cat Felis silvestris
Mouse Mus musculus Q8K441 1624 183252 S1549 A R Q D R C F S L L T Y K L P
Rat Rattus norvegicus Q8CF82 1642 185792 S1562 P N A S R Q E S F S S I L A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509469 1722 195635 S1642 P N A S R Q E S F S S I L A Y
Chicken Gallus gallus XP_415691 1546 175373 S1472 A R Q E R F P S L L V Y K V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092716 1654 185619 T1566 V R Q D S F A T L M V Y K I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 T1631 S V L K T T S T N K T L N L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 S1720 N V P T Q P R S L L G D L E V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 94.8 74.9 N.A. 67.3 40.7 N.A. 39.2 44 N.A. 40.5 N.A. N.A. N.A. 22.7 N.A.
Protein Similarity: 100 96.2 96.9 84.5 N.A. 80.7 61 N.A. 59.2 62.4 N.A. 61 N.A. N.A. N.A. 43.5 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 73.3 13.3 N.A. 13.3 66.6 N.A. 33.3 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 80 20 N.A. 20 80 N.A. 73.3 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 19 0 0 0 10 0 0 0 0 0 0 19 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 46 0 0 19 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 19 10 0 19 0 0 0 0 0 0 % F
% Gly: 0 28 0 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 19 0 10 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 10 0 0 64 0 10 % K
% Leu: 0 0 10 0 0 0 0 0 73 64 0 10 28 55 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 19 0 0 0 0 0 0 10 0 0 0 10 0 0 % N
% Pro: 19 0 10 0 0 10 10 0 0 0 0 0 0 0 64 % P
% Gln: 0 10 64 0 10 19 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 28 0 0 73 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 19 10 0 46 82 0 19 19 0 0 0 0 % S
% Thr: 0 0 0 10 10 10 0 19 0 0 46 0 0 0 0 % T
% Val: 10 19 0 0 0 0 0 0 0 0 28 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 37 0 0 0 0 0 64 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _